منابع مشابه
Ultrasound perfusion imaging of the human brain.
BACKGROUND AND PURPOSE Color-coded perfusion maps can be calculated from ultrasound harmonic gray-scale imaging data to analyze brain tissue perfusion. METHODS In 13 healthy volunteers, 2 doses (0.5 and 1.5 mL) of Optison, a perfluoropropane-containing ultrasound contrast agent, were injected intravenously, and they produced a strong increase in echo enhancement in the brain parenchyma. The c...
متن کاملImaging tumor hypoxia and tumor perfusion.
Tumor perfusion and oxygenation status have been suggested as factors which may influence treatment outcome in cancer patients. Nuclear medicine assays of tumor perfusion [99mTc-hexamethylpropylenamine oxime (HMPAO)] and tumor hypoxia [123I-iodoazomycin arabinoside (IAZA)] have recently been developed and described. We report on measurements of perfusion and oxygenation status of 27 tumors in 2...
متن کاملImaging Tumor Microenvironment with Ultrasound
Recent advances in molecular biology are providing new opportunities for breast cancer imaging. Our approach uses ultrasound to image viscoelastic features of tumors. These features describe microenvironmental factors that stimulate signaling pathways in tumors that ultimately affect metastatic potential and response to traditional therapeutics. This paper explains the motivation for the approa...
متن کاملMultimodality Imaging of Tumor Angiogenesis: Perfusion Modeling for Tumor Angiogenesis
When a tracer, such as Gd-doped or iodinated extracellular contrast, is introduced into the blood stream of a patient its transport through the vascular system, heart and lungs and eventual excretion via the kidneys is a well-established process [1,2]. At the level of the imaging voxel (for example, in the centre of a breast tumor) we can only speculate as to the precise nature of the tracer ki...
متن کاملDoppler ultrasound imaging detects changes in tumor perfusion during antivascular therapy associated with vascular anatomic alterations.
Noninvasive monitoring of antiangiogenic therapy was performed by serial power Doppler ultrasound imaging of murine tumors treated with recombinant interleukin 12, the results of which were correlated with assessments of tumor vascularity by microscopy. Growth of established K1735 tumors, but not of IFN-gamma-unresponsive K1735.N23 variants, was suppressed by treatment. Serial Doppler imaging o...
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ژورنال
عنوان ژورنال: Breast Cancer Research
سال: 2003
ISSN: 1465-542X
DOI: 10.1186/bcr701